Low riskEurope · Southern EuropeHoly See (Vatican City State) Travel Health Guide
Low risk
Holy See (Vatican City State) carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
Overall risk
Low risk
Malaria
None
Best time to visit
Year-round
Recommended vaccines
Routine Vaccines
Make sure you're up-to-date on all routine vaccines including chickenpox, tetanus, flu, MMR, polio, and shingles.
COVID-19
Stay up-to-date with COVID-19 vaccines before traveling.
Hepatitis A
Consider hepatitis A vaccine if visiting smaller cities, rural areas, or eating street food.
Hepatitis B
Hepatitis B vaccine is recommended for unvaccinated travelers under 60, and may be considered for those 60 and older.
Measles
Measles cases are rising worldwide. All travelers need MMR vaccine at least 2 weeks before travel. Infants 6-11 months need an early dose.
Rabies
Rabid dogs are uncommon in Italy. Rabies vaccines are available if needed. Consider pre-exposure vaccination only if you'll have high-risk animal exposure or limited access to medical care.
Tick-borne Encephalitis
TBE vaccine is recommended if you'll have extensive outdoor activities with tick exposure in endemic areas of Italy.
Yellow Fever
Yellow fever vaccine is not recommended and not required for entry to Italy.
Disease risks
Emergency numbers
Police
112
Medical / Ambulance
118
Fire
115
U.S. Embassy
+39-06-4674-3428
Holy See (Vatican City State) travel health FAQ
Do I need vaccines to travel to Holy See (Vatican City State)?▼
For travel to Holy See (Vatican City State), Routine Vaccines, COVID-19, Hepatitis A, Hepatitis B and Measles are recommended; Rabies, Tick-borne Encephalitis and Yellow Fever may be advised depending on your itinerary. Make sure your routine vaccinations (such as MMR, Tdap, polio and seasonal flu) are up to date, and see a travel-health provider about 4–6 weeks before you leave.
Is there malaria in Holy See (Vatican City State)?▼
No — Holy See (Vatican City State) is not considered a malaria-risk destination, so antimalarial medication is not routinely needed. Basic insect-bite precautions are still sensible.
Is it safe to travel to Holy See (Vatican City State)?▼
From a travel-health standpoint, Holy See (Vatican City State) is currently rated low risk. Holy See (Vatican City State) carries a CDC Level 1 travel health notice. No malaria risk. Key travel vaccines: COVID-19, Hepatitis A, Hepatitis B.
What are the emergency phone numbers in Holy See (Vatican City State)?▼
Key emergency numbers in Holy See (Vatican City State) are Police 112, Medical / Ambulance 118, Fire 115 and U.S. Embassy +39-06-4674-3428. Save them before you travel and confirm the current numbers with your accommodation on arrival.
More country guides
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Build my Trip KitSources: CDC Travelers' Health · WHO International Travel and Health. Last updated 2026-07-31. Health conditions and entry rules change — verify with the CDC, WHO and your destination’s authorities before travel. This page is informational and not a substitute for advice from a travel-medicine provider.